Tablet Presentation

Each uncoated bilayer tablet contains:
Teneligliptin Hydrobromide Hydrate IP
Equivalent to Teneligliptin 20 mg
Metformin Hydrochloride  (as sustained release ) IP 500 mg

Diabetes may cause many complications and causes disability, reduces the quality of living and premature death.so, this composition offers benefits and effectively treats short term and long-term complications.

Indications

In type-2 diabetes mellitus

About Composition

Teneligliptin:

Teneligliptin is a dipeptidyl peptidase 4 inhibitor. It is used along with exercise and diet for the control of blood sugar level

Metformin Hydrochloride:

Metformin is a biguanide and it prevents the damage of kidney and blindness and problems in nerves, loss of limbs and sexual functional problems.

Mechanism of Action

Teneligliptin:

It increases the release of insulin from the pancreas and causes the decrease in the release of hormone that raises the blood sugar levels.

Metformin:

It delays the absorption of glucose from the intestine and increases the sensitivity to insulin or lowers the production of glucose from liver.

Pharmacokinetics

Absorption: It is absorbed via GIT
Protein Binding: It is 90% bound to plasma proteins
Metabolism: It is metabolized in the liver
Excretion: It is excreted via urine

Side Effects

• Nausea
• Vomiting
• Stomach upset
• Sore throat
• Congestion of nose

Contraindications

• Contraindicated in people with renal impairment
• Contraindicated in people with known hypersensitivity

Drug Interactions

• Atenolol
• Metoprolol
• Vandetanib

Disclaimer:The data uploaded is made from content already available on internet.The company holds no right of it and is not responsible for any wrong information.